Bioinformatics PhD Position – Computational Immunology (f/m/d)
Department of Medicine 3
Prof. Dr. med. Andreas Ramming
Ulmenweg 18
91054 Erlangen
Dr. Hashem Mohammadian
Postdoctoral Researcher
Telefon: 09131 85-39592
Postdoctoral Researcher
Telefon: 09131 85-39592
Department of Medicine 3
Prof. Dr. med. Andreas Ramming
Ulmenweg 18
91054 Erlangen
Job-Nr.: 12900
Department of Medicine 3
Prof. Dr. med. Andreas Ramming
Ulmenweg 18
91054 Erlangen
Dr. Hashem Mohammadian
Postdoctoral Researcher
Telefon: 09131 85-39592
Mit Dienstzeiten, die zu
Deinem Leben passen!
We investigate autoimmune diseases, including inflammatory arthritis and fibrotic diseases, with a focus on mesenchymal activation in inflammation-driven immune disease. Computational analysis is a core component of our work, enabling discovery across multi-omics datasets and supporting publication-driven research. Check out our recent relevant publications:
Skin-derived myeloid precursors and joint-resident fibroblasts spread psoriatic disease from skin to joints
CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis
Matrix stiffness regulates profibrotic fibroblast differentiation and fibrotic niche activation in systemic sclerosis
Our laboratory has access to advanced single-cell and spatial profiling technologies, including single-cell RNA-seq, spatial transcriptomics (Visium/MERSCOPE) and imaging mass cytometry (IMC), alongside established in vitro and in vivo model systems and close links to clinical research. You will work with complex datasets in an environment that values rigorous, reproducible computational science.
We are looking for a motivated PHD candidate (f/m/d) to join our bioinformatics team. In this role, you will contribute to ongoing and new computational projects, develop reproducible analysis workflows, and support data-driven discovery across our research program.
Tasks
- Analyze high-dimensional multi-omics datasets (including single-cell and spatial data) using state-of-the-art computational methods.
- Develop, implement, and maintain reproducible analysis pipelines (QC, integration, statistics, visualization, reporting).
- Apply statistical and machine learning methods to generate robust biological insights.
- Curate and manage data and metadata to ensure reproducibility, traceability, and efficient downstream analysis.
- Contribute to scientific outputs, including figures, methods, and text for manuscripts and presentations.
Qualification
- Master’s degree (or equivalent; completed by the start date) in Bioinformatics, Computer Science, Data Science, Computational Biology, or a related discipline.
- Basic understanding of immunology / molecular biology.
- Strong programming skills in R and Python.
- Practical experience with high-dimensional data analysis (omics preferred).
- Solid understanding of statistics.
- Strong analytical thinking, attention to detail, and ability to work independently.
- Excellent written and spoken English.
- Working hours: 65% to 100% (based on level of experience)
- Please add a cover letter stating your motivation and fit to the role, CV and transcripts to your application.
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